Hilton Orlando – Florida Ballroom 1-4 | Supported By: An educational grant from AstraZeneca

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Program Description

Join us for dinner and a dynamic Mechanisms to Medicine symposium featuring expert panelists Drs. Joseph Han, Flavia Hoyte, and Nizar Jarjour as they examine evolving management approaches for epithelial cytokine–driven inflammatory diseases of the upper and lower airways. This program brings together multidisciplinary perspectives from pulmonology, allergy and immunology, and otorhinolaryngology to explore shared underlying disease mechanisms in asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and chronic obstructive pulmonary disease (COPD).

The engaging faculty panel will guide participants through an examination of epithelial cytokine signaling in airway diseases and practical therapeutic decision-making involving new and emerging biologic therapies that target these shared upstream mechanisms. Through a focused Whiteboard animation, case-based checkpoints, and interactive faculty dialogue, learners will examine how epithelial alarmins such as thymic stromal lymphopoietin (TSLP), interleukin-25 (IL-25), and interleukin-33 (IL-33) drive inflammation, airway dysfunction, and disease persistence.

Attendees will also learn about the latest clinical evidence for newer and emerging biologic therapies that target upstream epithelial cytokine signaling and discuss how to incorporate these novel therapies into mechanism-based treatment strategies, with an emphasis on optimizing disease control, reducing oral corticosteroid use, and improving outcomes across the unified airway.

This program was developed by, or with financial support and influence from, Integritas Communications and is neither sponsored by nor endorsed by ATS.

Speakers

Presenter: Nizar Jarjour, MD, ATSF
University of Wisconsin School of Medicine and Public Health
Ovid Meyer Endowed Professor of Medicine
Madison, Wisconsin

Presenter: Joseph Han, MD, FARS, FAAOA
Eastern Virginia Medical School
Professor of Otolaryngology
Norfolk, Virginia

Presenter: Flavia Hoyte, MD
National Jewish Health/University of Colorado
Division of Allergy and Immunology
Professor of Medicine
Denver, Colorado