Turning Down the Inflammatory Signal in COPD: Advancing Care With Biologic Therapies Targeting Upstream Cytokines

May 17 @ 6:30 pm 7:45 pm EDT

Hyatt Regency Orlando, Windemere Ballroom X (Conference Level) | Provided By: PVI, PeerView Institute for Medical Education and Supported by: An educational grant from Genentech


Program Description

Chronic obstructive pulmonary disease (COPD) encompasses a group of progressive and inflammatory lung diseases characterized by persistent respiratory symptoms and exacerbations resulting in decreased quality of life (QOL), hospitalization, irreversible lung damage, and progressively declining lung function. Conventional COPD treatment includes inhaled long-acting bronchodilators and steroids, but many patients continue to experience poor symptom control and frequent exacerbations.

Therapeutic advancements have significantly transformed COPD care, with biologics—initially developed for type 2 inflammatory diseases like asthma—now being repurposed to target these shared type 2 inflammatory pathways in COPD. However, currently approved biologic therapy in COPD only targets eosinophilic inflammation, which accounts for a small subpopulation of patients with COPD. Fortunately, groundbreaking advances identified an upstream target—ST2/IL33—potentially impacting both eosinophilic and neutrophilic inflammation in COPD; this will provide opportunities for personalizing treatment and overcoming limitations of current therapies in a broader patient population (eg, patients with low eosinophils).

With the goal of helping clinicians adapt their practice in alignment with the growing role of biologics in the COPD treatment armamentarium, PeerView has prepared this Peer Pressure educational symposium. Our panel will discuss the latest data on integrating targeted biologics into updated treatment protocols and recent evidence on emerging options, factoring in safety, patient preferences, and QOL for patients with COPD. In this lively format, the experts will be put on the spot with clinical questions that spark spirited discussion, reveal key insights, and offer real-world guidance. Join us live—in Orlando or online—and see if you can keep up!

This CME/MOC/AAPA activity is provided by PVI, PeerView Institute for Medical Education, and supported by an educational grant from Genentech, a member of the Roche Group.

Speakers

Chair & Moderator: Cedric “Jamie” Rutland, MD
IM, Pulmonary and Critical Care
National Spokesperson, American Lung Association
Rutland Medical Group, CEO and Medical Director
Medicine Deconstructed Productions, President
Newport Beach, California

Presenter: Stephanie Christenson, MD, MAS
Associate Professor of Medicine
Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine
University of California, San Francisco
San Francisco, California

Presenter: MeiLan K. Han, MD, MS
Chief, Pulmonary & Critical Care
University of Michigan
Ann Arbor, Michigan

Presenter: Vickram Tejwani, MD
Assistant Professor
Departments of Pulmonary and Critical Care Medicine
Genomic Science and Systems Biology
Cleveland Clinic Lerner College of Medicine
Cleveland, Ohio